HUMORAL & CELL MEDIATED RESPONSE OF IMMUNE SYSTEM

GOOD MORNING BOYS .
MARK YOUR ATTENDANCE FIRST.


Today we will achieve the following LEARNING OUTCOMES:
Students will be able to :

1. Understand & Analyse the various response our immune system develops to any invasion of pathogen.

2. Draw & Label the Structure of ANTIBODY.

3. List various types of Antibodies formed in our body.


GENERAL INSTRUCTIONS:

1. WRITE YOUR NOTES IN YOUR REGISTER WITH LABEL DIAGRAMS OF ANTIBODY.

2. THERE IS ONLY 1 YOUTUBE VIDEO LINK SENT WITH THIS BLOG . KINDLY WATCH IT BEFORE READING THE BLOG.

3. ASK YOUR DOUBTS  ON OUR WATSAPP GROUP.







LET'S BEGIN.



Just to remind you in the last class we did different types of IMMUNITY.

Based on the type of immune cell acting against the antigens, immunity can be classified into two types-

• Humoral immunity- the immunity which is mediated by antibodies produced by B-lymphocytes is called humoral immunity.
• Cell- mediated immunity- The immunity which is mediated by T- lymphocytes by directly attaching themselves to the antigens is called cell mediated immunity.

STRUCTURE OF ANTIBODY

Each antibody molecule has four peptide chains, two long chains and two short chains arranged in a Y shaped structure.

Two long chains are called heavy chains and two short chains are called light chains, hence an antibody is represented as H2L2.

Antibodies are also called as immunoglobulins (Ig).

Different types of antibodies are produced in our bodies which are IgA, IgM, IgE, IgG.

TYPES OF IMMUNE RESPONSES DEVELOPED BY OUR SYSTEM TO THE INVASION OF ANY MICRO-ORGANISMS.





Immune Response:

The immune response involves primary immune response and secondary immune response.

(a) The primary immune response:

After an initial contact with an antigen, no anti­bodies are present for a period of several days. Then, a slow rise in the antibody titer (arbitrary units) occurs, first IgM and then IgG followed by a gradual decline in antibody titer. This is called the primary immune response.

(b) The secondary immune response:

Memory cells may remain in the body for decades. Every new encounter with the same antigen results in a rapid proliferation of memory cells. This is also called “booster response”. The antibody titer after subsequent encounters is far greater than during a primary response and consists mainly of IgG anti­bodies. This accelerated, more intense response is called the secondary immune response. Antibodies produced during a secondary response have an even higher affinity for the antigen.

The increased power and duration of the secondary immune response explain why immunization (called vaccination) is usually accomplished by injecting antigen in multiple doses.

HOMEWORK TASK :

1. Distinguish between VACCINATION & IMMUNISATION.  (3 marks)

2. List various Immunisation programmes organised by INDIAN GOVERNMENT & for what diseases.

No need to send the answers to me on mail . I will  ask for the homework submission ,once More questions are added to it from other topics also.

I'll see you tomorrow according to DAY 2 time table.

see you now for RS.